Immune barrier may explain why mRNA shots struggle to block nasal infection

Article excerpt

Researchers from the University of Surrey and University College London have identified a biological barrier that prevents the immune system from producing antibodies needed to protect the nose and throat from respiratory viruses. This discovery could explain why mRNA vaccines struggle to block nasal infections at their point of entry. The finding points toward designing next-generation vaccines that overcome this immune obstacle, potentially improving protection against respiratory pathogens before they establish infection.