Engineered stem cells reverse new-onset type 1 diabetes in mice

Article excerpt

Researchers at the Medical University of South Carolina have engineered stem cells that reverse new-onset type 1 diabetes in mice, according to findings published in Molecular Therapy. The therapy represents a potential breakthrough for a disease that affects millions worldwide and typically requires lifelong insulin management. The work demonstrates that the engineered cells can restore the body's ability to produce insulin naturally, at least in the early stages of the disease. While the results are promising, the research remains in preclinical stages, the next hurdle is determining whether the approach will translate to human patients.