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Opinion: New human embryo editing advances require tough conversations on ethical boundaries

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What if you could precisely change the genome of a pre-implantation human embryo and then safely use that embryo to try to generate a healthier person? It’s a wild idea, but one that technology over the past decade has steadily made a bit less fantastical, at least practically speaking. But even as CRISPR gene-editing research has advanced, including exciting work reported in a new preprint on base editing of human embryos from geneticist Dieter Egli’s lab at Columbia, the same tough ethical questions remain. Read the rest…