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Parkinson's medication shows promise in treating treatment-resistant depression

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A Swedish study published in Nature Medicine reveals that pramipexole, a medication traditionally used for Parkinson's disease, may help patients with treatment-resistant depression, particularly those struggling with apathy and anhedonia, the loss of pleasure in once-enjoyed activities. The drug works as an add-on therapy for people whose depression hasn't responded to standard antidepressants. The finding opens a new avenue for treating a stubborn form of depression that affects millions and leaves them not just sad but unmotivated and emotionally numb.