SCD1 enzyme in lipid metabolism sheds light on resistance of certain cancers to treatment

Article excerpt

The Cancer Metabolism and Tumor Microenvironment Laboratory at the University of Liège has uncovered a previously unrecognized mechanism that promotes cancer cell survival under therapeutic pressure. Published in MedComm, the study shows how a key enzyme in lipid metabolism, stearoyl-CoA desaturase-1 (SCD1), cooperates with an epigenetic regulator to support tumor growth.